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Association between cigarette smoking and the prevalence of post-endodontic periapical pathology: a systematic review and meta-analysis

Restorative Dentistry & Endodontics 2022³â 47±Ç 3È£ p.27 ~ 27
Rios-Osorio Nestor, Munoz-Alvear Hernan Dario, Jimenez-Castellanos Fabio Andres, Quijano-Guauque Sara, Jimenez-Pena Oscar, Garcia-Perdomo Herney Andres, Caviedes-Bucheli Javier,
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 ( Rios-Osorio Nestor ) - Institucion Universitaria Colegios de Colombia UNICOC Research Department COC-CICO
 ( Munoz-Alvear Hernan Dario ) - Universidad Cooperativa de Colombia Department of Endodontics
 ( Jimenez-Castellanos Fabio Andres ) - Universidad Antonio Narino Department of Periodontics
 ( Quijano-Guauque Sara ) - Institucion Universitaria Colegios de Colombia UNICOC Research Department COC-CICO
 ( Jimenez-Pena Oscar ) - Institucion Universitaria Colegios de Colombia UNICOC Research Department COC-CICO
 ( Garcia-Perdomo Herney Andres ) - Universidad del Valle School of Medicine Department of Surgery and Urology
 ( Caviedes-Bucheli Javier ) - Pontificia Universidad Javeriana Centro de Investigaciones Odontologicas

Abstract


Objectives: This systematic review and meta-analysis aimed to assess the association of cigarette smoking with the prevalence of post-endodontic apical periodontitis in humans.

Materials and Methods: We searched through PubMed/Medline, Web of Science, and Scopus from inception to December 2020. Risk of bias was performed by using the Newcastle-Ottawa Scale for cross-sectional, cohort, and case-control studies. We performed the statistical analysis in Review Manager 5.3 (RevMan 5.3).

Results: 6 studies met the inclusion criteria for qualitative and quantitative synthesis. Statistical analysis of these studies suggests that there were no differences in the prevalence of post endodontic apical periodontitis (AP) when comparing non-smokers vs smoker subjects regarding patients (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.31?1.49; I2 = 58%) and teeth (OR, 1.71; 95% CI, 0.99?2.93; I2 = 72%).

Conclusions: Our findings suggest that there was no association between cigarette smoking and post-endodontic apical periodontitis, as we did not find statistical differences in the prevalence of post-endodontic AP when comparing non-smokers vs smoker subjects. Therefore, smoking should not be considered a risk factor associated with endodontic failure.

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Root canal treatment; Apical periodontitis; Cigarette smoking; Systematic review

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